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Class definition of 'YAEL' image pipeline

Source: R/class-YAEL.R
YAELProcess.Rd

Rigid-registration across multiple types of images, non-linear normalization from native brain to common templates, and map template atlas or 'ROI' back to native brain. See examples at as_yael_process

Value

whether the image has been set (or replaced)

Absolute path if the image

'RAVE' subject instance

Nothing

A list of moving and fixing images, with rigid transformations from different formats.

See method get_template_mapping

A list of input, output images, with forward and inverse transform files (usually two 'Affine' with one displacement field)

transformed image in 'ANTs' format

transformed image in 'ANTs' format

Nothing

A matrix of 3 columns, each row is a transformed points ( invalid rows will be filled with NA)

A matrix of 3 columns, each row is a transformed points ( invalid rows will be filled with NA)

Active bindings

subject_code

'RAVE' subject code

work_path

Working directory ('RAVE' imaging path)

Methods

Public methods

Method new()

Constructor to instantiate the class

Usage

YAELProcess$new(subject_code)

Arguments

subject_code

character code representing the subject

Method set_input_image()

Set the raw input for different image types

Usage

YAELProcess$set_input_image(
  path,
  type = c("T1w", "T2w", "CT", "FLAIR", "preopCT", "T1wContrast", "fGATIR"),
  overwrite = FALSE,
  on_error = c("warning", "error", "ignore")
)

Arguments

path

path to the image files in 'NIfTI' format

type

type of the image

overwrite

whether to overwrite existing images if the same type has been imported before; default is false

on_error

when the file exists and overwrite is false, how should this error be reported; choices are 'warning' (default), 'error' (throw error and abort), or 'ignore'.

Method get_input_image()

Get image path

Usage

YAELProcess$get_input_image(
  type = c("T1w", "T2w", "CT", "FLAIR", "preopCT", "T1wContrast", "fGATIR")
)

Arguments

type

type of the image

Method get_subject()

Get 'RAVE' subject instance

Usage

YAELProcess$get_subject(project_name = "YAEL", strict = FALSE)

Arguments

project_name

project name; default is 'YAEL'

strict

passed to as_rave_subject

Method register_to_T1w()

Register other images to 'T1' weighted 'MRI'

Usage

YAELProcess$register_to_T1w(
  image_type = c("CT", "T2w", "FLAIR", "preopCT", "T1wContrast", "fGATIR"),
  reverse = FALSE,
  verbose = TRUE
)

Arguments

image_type

type of the image to register, must be set via process$set_input_image first.

reverse

whether to reverse the registration; default is false, meaning the fixed (reference) image is the 'T1'. When setting to true, then the 'T1' 'MRI' will become the moving image

verbose

whether to print out the process; default is true

Method get_native_mapping()

Get the mapping configurations used by register_to_T1w

Usage

YAELProcess$get_native_mapping(
  image_type = c("CT", "T2w", "FLAIR", "preopCT", "T1wContrast", "fGATIR"),
  relative = FALSE
)

Arguments

image_type

type of the image registered to 'T1' weighted 'MRI'

relative

whether to use relative path (to the work_path field)

Method map_to_template()

Normalize native brain to 'MNI152' template

Usage

YAELProcess$map_to_template(
  template_name = c("mni_icbm152_nlin_asym_09a", "mni_icbm152_nlin_asym_09b",
    "mni_icbm152_nlin_asym_09c"),
  native_type = c("T1w", "T2w", "CT", "FLAIR", "preopCT", "T1wContrast", "fGATIR"),
  verbose = TRUE
)

Arguments

template_name

which template to use, choices are 'mni_icbm152_nlin_asym_09a', 'mni_icbm152_nlin_asym_09b', 'mni_icbm152_nlin_asym_09c'.

native_type

which type of image should be used to map to template; default is 'T1w'

verbose

whether to print out the process; default is true

Method get_template_mapping()

Get configurations used for normalization

Usage

YAELProcess$get_template_mapping(
  template_name = c("mni_icbm152_nlin_asym_09a", "mni_icbm152_nlin_asym_09b",
    "mni_icbm152_nlin_asym_09c"),
  native_type = c("T1w", "T2w", "CT", "FLAIR", "preopCT", "T1wContrast", "fGATIR"),
  relative = FALSE
)

Arguments

template_name

which template is used

native_type

which native image is mapped to template

relative

whether the paths should be relative or absolute; default is false (absolute paths)

Method transform_image_from_template()

Apply transform from images (usually an atlas or 'ROI') on template to native space

Usage

YAELProcess$transform_image_from_template(
  template_roi_path,
  template_name = c("mni_icbm152_nlin_asym_09a", "mni_icbm152_nlin_asym_09b",
    "mni_icbm152_nlin_asym_09c"),
  native_type = c("T1w", "T2w", "CT", "FLAIR", "preopCT", "T1wContrast", "fGATIR"),
  interpolator = c("auto", "nearestNeighbor", "linear", "gaussian", "bSpline",
    "cosineWindowedSinc", "welchWindowedSinc", "hammingWindowedSinc",
    "lanczosWindowedSinc", "genericLabel"),
  verbose = TRUE
)

Arguments

template_roi_path

path to the template image file which will be transformed into individuals' image

template_name

templates to use

native_type

which type of native image to use for calculating the coordinates (default 'T1w')

interpolator

how to interpolate the 'voxels'; default is "auto": 'linear' for probabilistic map and 'nearestNeighbor' otherwise.

verbose

whether the print out the progress

Method transform_image_to_template()

Apply transform to images (usually an atlas or 'ROI') from native space to template

Usage

YAELProcess$transform_image_to_template(
  native_roi_path,
  template_name = c("mni_icbm152_nlin_asym_09a", "mni_icbm152_nlin_asym_09b",
    "mni_icbm152_nlin_asym_09c"),
  native_type = c("T1w", "T2w", "CT", "FLAIR", "preopCT", "T1wContrast", "fGATIR"),
  interpolator = c("auto", "nearestNeighbor", "linear", "gaussian", "bSpline",
    "cosineWindowedSinc", "welchWindowedSinc", "hammingWindowedSinc",
    "lanczosWindowedSinc", "genericLabel"),
  verbose = TRUE
)

Arguments

native_roi_path

path to the native image file that will be transformed into template

template_name

templates to use

native_type

which type of native image to use for calculating the coordinates (default 'T1w')

interpolator

how to interpolate the 'voxels'; default is "auto": 'linear' for probabilistic map and 'nearestNeighbor' otherwise.

verbose

whether the print out the progress

Method generate_atlas_from_template()

Generate atlas maps from template and morph to native brain

Usage

YAELProcess$generate_atlas_from_template(
  template_name = c("mni_icbm152_nlin_asym_09a", "mni_icbm152_nlin_asym_09b",
    "mni_icbm152_nlin_asym_09c"),
  atlas_folder = NULL,
  surfaces = NA,
  verbose = TRUE
)

Arguments

template_name

which template to use

atlas_folder

path to the atlas folder (that contains the atlas files)

surfaces

whether to generate surfaces (triangle mesh); default is NA (generate if not existed). Other choices are TRUE for always generating and overwriting surface files, or FALSE to disable this function. The generated surfaces will stay in native 'T1' space.

verbose

whether the print out the progress

Method transform_points_to_template()

Transform points from native images to template

Usage

YAELProcess$transform_points_to_template(
  native_ras,
  template_name = c("mni_icbm152_nlin_asym_09a", "mni_icbm152_nlin_asym_09b",
    "mni_icbm152_nlin_asym_09c"),
  native_type = c("T1w", "T2w", "CT", "FLAIR", "preopCT", "T1wContrast", "fGATIR"),
  verbose = TRUE
)

Arguments

native_ras

matrix or data frame with 3 columns indicating points sitting on native images in right-anterior-superior ('RAS') coordinate system.

template_name

template to use for mapping

native_type

native image type where the points sit on

verbose

whether the print out the progress

Method transform_points_from_template()

Transform points from template images to native

Usage

YAELProcess$transform_points_from_template(
  template_ras,
  template_name = c("mni_icbm152_nlin_asym_09a", "mni_icbm152_nlin_asym_09b",
    "mni_icbm152_nlin_asym_09c"),
  native_type = c("T1w", "T2w", "CT", "FLAIR", "preopCT", "T1wContrast", "fGATIR"),
  verbose = TRUE
)

Arguments

template_ras

matrix or data frame with 3 columns indicating points sitting on template images in right-anterior-superior ('RAS') coordinate system.

template_name

template to use for mapping

native_type

native image type where the points sit on

verbose

whether the print out the progress

Method construct_ants_folder_from_template()

Create a reconstruction folder (as an alternative option) that is generated from template brain to facilitate the '3D' viewer. Please make sure method map_to_template is called before using this method (or the program will fail)

Usage

YAELProcess$construct_ants_folder_from_template(
  template_name = c("mni_icbm152_nlin_asym_09a", "mni_icbm152_nlin_asym_09b",
    "mni_icbm152_nlin_asym_09c"),
  add_surfaces = TRUE
)

Arguments

template_name

template to use for mapping

add_surfaces

whether to create surfaces that is morphed from template to local; default is TRUE. Please enable this option only if the cortical surfaces are not critical (for example, you are studying the deep brain structures). Always use 'FreeSurfer' if cortical information is used.

Method get_brain()

Get '3D' brain model

Usage

YAELProcess$get_brain(
  electrodes = TRUE,
  project_name = "YAEL",
  coord_sys = c("scannerRAS", "tkrRAS", "MNI152", "MNI305"),
  ...
)

Arguments

electrodes

whether to add electrodes to the viewers; can be logical, data frame, or a character (path to electrode table). When the value is TRUE, the electrode file under project_name will be loaded; when electrodes is a data.frame, or path to a 'csv' file, then please specify coord_sys on what is the coordinate system used for columns "x", "y", and "z".

project_name

project name under which the electrode table should be queried, if electrodes=TRUE

coord_sys

coordinate system if electrodes is a data frame with columns "x", "y", and "z", available choices are 'scannerRAS' (defined by 'T1' weighted native 'MRI' image), 'tkrRAS' ('FreeSurfer' defined native 'TK-registered'), 'MNI152' (template 'MNI' coordinate system averaged over 152 subjects; this is the common "'MNI' coordinate space" we often refer to), and 'MNI305' (template 'MNI' coordinate system averaged over 305 subjects; this coordinate system used by templates such as 'fsaverage')

...

passed to threeBrain

Method clone()

The objects of this class are cloneable with this method.

Usage

YAELProcess$clone(deep = FALSE)

Arguments

deep

Whether to make a deep clone.